Table 3 The 34 significant pathways found by JEPETTO (Cytoscape plugin) with KEGG database
Pathway | XD-score | q value | Overlap/size |
|---|---|---|---|
Linoleic acid metabolism | 3.148 | 0.000 | 10/11 |
Citrate cycle (TCA cycle) | 3.057 | 0.000 | 21/26 |
Propanoate metabolism | 1.899 | 0.000 | 11/19 |
Arachidonic acid metabolism | 1.865 | 0.000 | 17/26 |
PPAR signaling pathway | 1.794 | 0.000 | 22/39 |
Tyrosine metabolism | 1.475 | 0.001 | 9/17 |
Retinol metabolism | 1.474 | 0.009 | 6/12 |
Bladder cancer | 1.463 | 0.000 | 17/38 |
Ether lipid metabolism | 1.370 | 0.002 | 8/16 |
Metabolism of xenobiotics by cytochrome P450 | 1.313 | 0.001 | 10/20 |
Adipocytokine signaling pathway | 1.248 | 0.000 | 24/57 |
Drug metabolism: cytochrome P450 | 1.240 | 0.003 | 8/17 |
Fatty acid metabolism | 1.096 | 0.000 | 12/26 |
Pyruvate metabolism | 1.096 | 0.000 | 12/26 |
One carbon pool by folate | 1.057 | 0.018 | 5/10 |
Glyoxylate and dicarboxylate metabolism | 1.057 | 0.018 | 5/10 |
Fc epsilon RI signaling pathway | 1.040 | 0.000 | 23/65 |
Pancreatic cancer | 1.013 | 0.000 | 25/70 |
Steroid hormone biosynthesis | 0.990 | 0.027 | 6/15 |
GnRH signaling pathway | 0.969 | 0.000 | 32/83 |
Beta-Alanine metabolism | 0.924 | 0.007 | 7/15 |
Prostate cancer | 0.913 | 0.000 | 32/84 |
Tryptophan metabolism | 0.903 | 0.000 | 12/26 |
Long-term depression | 0.893 | 0.000 | 23/57 |
Toll-like receptor signaling pathway | 0.883 | 0.000 | 32/90 |
NOD-like receptor signaling pathway | 0.879 | 0.000 | 21/59 |
Biosynthesis of unsaturated fatty acids | 0.875 | 0.027 | 5/11 |
Riboflavin metabolism | 0.875 | 0.027 | 5/11 |
VEGF signaling pathway | 0.872 | 0.000 | 24/62 |
Glycerophospholipid metabolism | 0.829 | 0.002 | 13/35 |
Type II diabetes mellitus | 0.814 | 0.010 | 13/43 |
Chagas disease | 0.804 | 0.000 | 36/99 |
Selenoamino acid metabolism | 0.763 | 0.049 | 6/17 |
Renal cell carcinoma | 0.708 | 0.000 | 24/68 |