Skip to main content

Table 4 Chemical–protein interactions and related significant signaling pathways

From: Network pharmacological identification of active compounds and potential actions of Erxian decoction in alleviating menopause-related symptoms

Herb Compound Protein Pathway
HE Emodin (1,3,8-trihydroxy-6-methylanthracene-9,10-dione) HSD11B1 Steroid hormone biosynthesis
RMO Alcool methylique SULT2B1 Steroid hormone biosynthesis
CPC Phenanthrene(TCMSP don’t record IUPAC name) CYP1A1 Steroid hormone biosynthesis
RMO Caffeic acid ((Z)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid) COMT Steroid hormone biosynthesis
HE Quercetin(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one) CYP19A1 Steroid hormone biosynthesis
HE Quercetin-3-O-glucoside CYP1B1 Steroid hormone biosynthesis
HE Apigenin(5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one) PTK2 VEGF signaling pathway
RMO Hemo-sol((4R)-1-methyl-4-prop-1-en-2-ylcyclohexene) HRAS VEGF signaling pathway
HE/RA Kaempferol(3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one) MAPK1/AKT1/SRC VEGF signaling pathway
RMO Esculetin(6,7-dihydroxychromen-2-one) MAPK3 VEGF signaling pathway
RMO Citric acid(2-hydroxypropane-1,2,3-tricarboxylic acid) KRAS VEGF signaling pathway
HE Oleanolic acid((3-beta)-3-Hydroxyolean-12-en-28-oic acid) MAPK14 VEGF signaling pathway
RAS Adenine(7H-purin-6-amine) PTGS2 VEGF signaling pathway
HE Emodin(1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione) VEGFA VEGF signaling pathway
HE Luteolin(2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one) PIK3CB VEGF signaling pathway
RA 3,5,7-Trihydroxy-4′-methoxyl-8-prenylflavone-3-O-rhamnopyranoside CASP9 VEGF signaling pathway
RC/RMO Myristic acid PPP3CB/PPP3CA VEGF signaling pathway
RC/RMO/RAS Palmitic acid NOS3 VEGF signaling pathway
RAS Lecithin PLA2G4A VEGF signaling pathway
HE/RMO Lauric acid PIK3CA VEGF signaling pathway
RA Chinoinin(1,3,6,7-tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one) PLA2G2A VEGF signaling pathway
RAS 4-Methoxybenzoic acid PLA2G1B VEGF signaling pathway
RMO Nonanoic acid NFAT5/NFATC3 VEGF signaling pathway
RMO (9Z,12Z)-octadeca-9,12-dienoic acid PLA2G10/PLA2G5 VEGF signaling pathway
RC/RMO Myristic acid PPP3CC VEGF signaling pathway
Back to article page

Chinese Medicine

ISSN: 1749-8546

Contact us