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Table 5 Effects of CTS on FFA, MDA, GSH and ATPase in the livers of mice fed with HFD

From: Crude triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non-alcoholic fatty liver disease model

Parameter Control HFD HFD + Simvastatin HFD + CTS-100 HFD + CTS-200
FFA (μmol/g protein) 61.05 ± 12.49 94.70 ± 15.63## 91.73 ± 13.50 93.89 ± 10.81* 79.87 ± 11.18**
MDA (nmol/mg protein) 0.69 ± 0.34 3.19 ± 0.33## 1.88 ± 0.44 1.68 ± 0.54** 1.50 ± 0.38**
GSH (μg/mg protein) 2.65 ± 0.53 1.05 ± 0.24## 2.80 ± 0.59 2.55 ± 0.65** 2.61 ± 0.50**
Na+-K+-ATPase (mmol pi/g/h) 1.55 ± 0.19 1.79 ± 018# 1.57 ± 0.26 1.68 ± 0.10 1.60 ± 0.26*
Ca2+-Mg2+-ATPase (mmol pi/g/h) 1.65 ± 0.13 1.76 ± 0.11# 1.31 ± 0.14 1.55 ± 0.14** 1.42 ± 0.31**
  1. Values were expressed as the mean ± SD (n = 10). # P < 0.05, ## P < 0.01, HFD vs. control. P < 0.05, P < 0.01, HFD vs. simvastatin treatment. *P < 0.05, **P < 0.01, HFD vs. CTS treatment.