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Table 3 Enriched signaling pathways in LGDH and LKYD

From: Serum cytokine profiling analysis for zheng differentiation in chronic hepatitis B

Zhengs

Signaling pathways

−log P value

Cytokines

LGDH

Cytokine-cytokine receptor interaction

9.41

LIF, IL-4, IL-8, IL-18, IL-1β, IL-15, MIP-1α, CTACK, IP-10

Cytosolic DNA-sensing pathway

4.02

IL-18, IL-1β, MIP-1α, IP-10

Toll-like receptor signaling pathway

3.23

IL-8, IL-1β, MIP-1α, IP-10

Intestinal immune network for IgA production

2.50

IL-4, IL-15, CTACK

Chemokine signaling pathway

2.46

IL-8, MIP-1α, CTACK, IP-10

NOD-like receptor signaling pathway

2.30

IL-8, IL-18, IL-1β

Jak-STAT signaling pathway

1.54

LIF, IL-4, IL-15

LKYD

Cytokine-cytokine receptor interaction

2.58

IL-18, CTACK, IP-10

Cytosolic DNA-sensing pathway

1.67

IL-18, IP-10

Chemokine signaling pathway

1.14

CTACK, IP-10