Fig. 2

Cell morphological changes induced by CME. a Cells treated with various concentrations of CME (15, 25, 30, 40, and 50 μg/mL) for 24 h. b Cells treated with 25 μg/mL for 24, 48, and 72 h. The cells were fixed after CME treatment, stained with HO 33258, and their nuclear morphology was photographed under fluorescence using a blue filter (×400). The arrow points to an apoptotic body