Efficacy of combining oral Chinese herbal medicine and NB-UVB in treating psoriasis vulgaris: a systematic review and meta-analysis

Table 4 Summary of findings

Oral CHM + NB-UVB compared to NB-UVB for psoriasis vulgaris
Participant or population: participants with psoriasis vulgaris
Settings: hospitals in China
Intervention: oral CHM + NB-UVB
Comparison: NB-UVB

Outcomes	Illustrative comparative risks (95 % CI)		Relative effect (95 % CI)	No. of participants (studies)	Quality of the evidence (GRADE)
	Assumed risk	Corresponding risk
	NB-UVB	Oral CHM + NB-UVB
PASI 60	Study population		RR 1.35 (1.26–1.45)	1339 (17 studies)	⊕ ⊕ ⊝⊝ low ^a,b
Follow-up 4–12 weeks	591 per 1000	797 per 1000 (744–857)
	Moderate
	633 per 1000	855 per 1000 (798–918)
PASI 90	Study population		RR 1.71 (1.45–2.01)	1342 (17 studies)	⊕ ⊕ ⊝⊝ low
Follow-up 4–12 weeks	219 per 1000	375 per 1000 (318–441)
	Moderate
	233 per 1000	398 per 1000 (338–468)

GRADE Working Group grades of evidence
High quality: further research is very unlikely to change our confidence in the estimate of effect
Moderate quality: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate
Low quality: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate
Very low quality: we are very uncertain about the estimate
^aBlindness of participants and investigators is “high risk” in all studies
^bAsymmetrical funnel plot and result of Egger’s test indicated potential publication bias

ISSN: 1749-8546