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Table 2 The inhibitory effects of ADHC-AXpn and DHC-Xpn on the viability of human carcinoma cells

From: Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells

  ADHC-AXpn (IC50, μM) DHC-Xpn (IC50, μM) Dox
24 h 48 h 24 h 48 h 48 h
MCF-7 30.32 ± 0.79 27.81 ± 1.29 >50 42.14 ± 4.63 4.07 ± 1.33
HepG2 40.73 ± 1.46 35.65 ± 1.17 >50 42.51 ± 2.57 3.80 ± 0.95
HepG2/ADM 33.66 ± 3.64 29.61 ± 0.26 >50 >50 143.47 ± 4.76
HeLa 41.25 ± 0.23 35.73 ± 2.15 >50 >50 4.62 ± 1.37
PC3 >50 >50 >50 >50 5.52 ± 1.19