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Table 2 The inhibitory effects of ADHC-AXpn and DHC-Xpn on the viability of human carcinoma cells

From: Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells

 

ADHC-AXpn (IC50, μM)

DHC-Xpn (IC50, μM)

Dox

24 h

48 h

24 h

48 h

48 h

MCF-7

30.32 ± 0.79

27.81 ± 1.29

>50

42.14 ± 4.63

4.07 ± 1.33

HepG2

40.73 ± 1.46

35.65 ± 1.17

>50

42.51 ± 2.57

3.80 ± 0.95

HepG2/ADM

33.66 ± 3.64

29.61 ± 0.26

>50

>50

143.47 ± 4.76

HeLa

41.25 ± 0.23

35.73 ± 2.15

>50

>50

4.62 ± 1.37

PC3

>50

>50

>50

>50

5.52 ± 1.19