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Fig. 3 | Chinese Medicine

Fig. 3

From: A novel coumarin, (+)-3′-angeloxyloxy-4′-keto-3′,4′-dihydroseselin, isolated from Bupleurum malconense (Chaihu) inhibited NF-κB activity

Fig. 3

Effect of Pd-Ib on inhibited the IκB-α degradation in LPS-stimulated RAW-Blue cells. After macrophages were treated with 1 μg/mL of LPS in absence or presence of various concentrations of Pd-Ib (5, 10 and 20 μg/mL) for 20 h, the protein level of IκB-α was determined by western blotting, β-actin was used as a loading control. a Representative image of western blotting. b The protein level of IκB-α was calculated with ImageJ software. Data were derived from three independent experiments and presented as mean ± SD. # Compared with the control group. *P < 0.05 and **P < 0.01 vs. LPS-alone group

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