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Table 2 In vitro IKK-β inhibitory activity (%) of compounds 1, 2 and berberine

From: Inhibition of IKK-β by epidioxysterols from the flowers of Calotropis gigantea (Niu jiao gua)

Concentration (µM)

IKK-β inhibitory activity (%)

Compound 1

Compound 2

Berberine

1

9.6 (2.7)

15.8 (1.5)

13.0 (4.3)

10

18.2 (4.5)

17.9 (3.5)

14.0 (4.2)

50

24.4 (3.9)

24.0 (1.7)

17.4 (2.7)

100

37.1 (1.1)

30.2 (2.6)

21.7 (1.8)

  1. The results are mean (SD) from three independent experiments