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Table 1 Effect of SHINBARO on change in body weight of MIA-induced OA rat model

From: Effects of intra-articular SHINBARO treatment on monosodium iodoacetate-induced osteoarthritis in rats

Days after treatment Control MIA
Vehicle Intra-articular SHINBARO (mg/kg) Oral SHINBARO (mg/kg) Diclofenac (5 mg/kg)
2 10 20 20 200
0th 305.5 ± 7.9 308.1 ± 20.4 301.2 ± 17.1 305.5 ± 11.8 306.2 ± 11.8 306.2 ± 14.5 306.0 ± 16.2 288.0 ± 13.9
7th 352.9 ± 11.6 347.6 ± 14.2 335.0 ± 14.5 352.2 ± 15.0 347.2 ± 10.7 347.3 ± 11.7 351.2 ± 12.7 317.8 ± 32.0
14th 384.5 ± 9.5 378.6 ± 17.1 365.2 ± 16.1 387.8 ± 14.1 379.3 ± 11.5 376.2 ± 11.4 387.0 ± 11.7 356.0 ± 15.5
21st 411.5 ± 15.2 402.0 ± 16.3 385.5 ± 19.7 411.5 ± 15.5 401.3 ± 12.0 395.8 ± 17.3 407.8 ± 13.1 388.5 ± 9.05
  1. SHINBARO or diclofenac was treated daily for 21 days after 2 weeks of OA induction by intra-articular injection of MIA. Body weight was measured once every 7 days after treatment of samples. Data represent as the mean ± SD (n = 6)