Table 1 Effect of SHINBARO on change in body weight of MIA-induced OA rat model
Days after treatment | Control | MIA | ||||||
|---|---|---|---|---|---|---|---|---|
Vehicle | Intra-articular SHINBARO (mg/kg) | Oral SHINBARO (mg/kg) | Diclofenac (5Â mg/kg) | |||||
2 | 10 | 20 | 20 | 200 | ||||
0th | 305.5 ± 7.9 | 308.1 ± 20.4 | 301.2 ± 17.1 | 305.5 ± 11.8 | 306.2 ± 11.8 | 306.2 ± 14.5 | 306.0 ± 16.2 | 288.0 ± 13.9 |
7th | 352.9 ± 11.6 | 347.6 ± 14.2 | 335.0 ± 14.5 | 352.2 ± 15.0 | 347.2 ± 10.7 | 347.3 ± 11.7 | 351.2 ± 12.7 | 317.8 ± 32.0 |
14th | 384.5 ± 9.5 | 378.6 ± 17.1 | 365.2 ± 16.1 | 387.8 ± 14.1 | 379.3 ± 11.5 | 376.2 ± 11.4 | 387.0 ± 11.7 | 356.0 ± 15.5 |
21st | 411.5 ± 15.2 | 402.0 ± 16.3 | 385.5 ± 19.7 | 411.5 ± 15.5 | 401.3 ± 12.0 | 395.8 ± 17.3 | 407.8 ± 13.1 | 388.5 ± 9.05 |