Fig. 1

Nuclei morphological change of HepG2 cells stained with DAPI fluorescent dye at 24 h. a Untreated HepG2 cells; b 80 μg/mL of melphalan; c 500 μg/mL of L. coromandelica (twig) extract; d 500 μg/mL of C. tomentosa (twig) extract; e 400 μg/mL of E. succirubrum (twig) extract; f 300 μg/mL of D. castanea (leaf) extract; g 300 μg/mL of D. castanea (twig) extract; and h 400 μg/mL of B. anceps (twig) extract. Arrows indicate apoptotic nuclei based on heterogeneous staining, DNA condensation, and apoptotic bodies at ×40 objective magnification