Fig. 9

Representative light microscopic appearances of the pancreas stained with H&E (200x) (a–d). a Normal histological changes were observed in the normal group on day 14. b Only minimal histological changes were observed in the control (high-fat and high-sugar) group on day 14. c The pancreatic ductal hypertension STZ-fat-diabetic rats group, infiltration of inflammatory cells were found in the interlobular and periductal areas on day 14. The pancreas was atrophic, and fibrosis and inflammatory cells were markedly distributed in the interlobular and interlobular areas. d In contrast, distributions of inflammatory cells and fibrosis were slightly noted Leukocyte infiltration in the catalpol group on day 14. The arrows represent inflammatory cells infiltration