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Table 5 Fluorogold immunolabeling

From: Chi-Ju-Di-Huang-Wan protects rats against retinal ischemia by downregulating matrix metalloproteinase-9 and inhibiting p38 mitogen-activated protein kinase

Group 1 2 3 4
RGCs (number/mm2) On day 1 1952.16 ± 125.29 929.01 ± 135.00** 1112.65 ± 164.10 1691.36 ± 237.57††
RGCs (number/mm2) On day 7 1737.23 ± 151.94 887.73 ± 158.18** 941.89 ± 38.91 1389.02 ± 53.20††
  1. In comparison of the control retina, 1 or 7 days following sham procedure (Sham; Group 1), after retinal ischemia plus 1 or 7 days of reperfusion and pretreatment with vehicle (I/R + Vehicle; Group 2), the number of fluorogold-immunolabeling retinal ganglion cells (RGCs) per field was significantly decreased (** P < 0.01). In contrast, this significant decrease was dose-dependently (with a less effect at 2.8 g/kg/day, I/R + CJDHW2.8; Group 3) and significantly (†† P < 0.01; at 4.2 g/kg/day, I/R + CJDHW4.2; Group 4) inhibited by pretreatment with CJDHW. The results are the mean ± SD (μm; n = 3)