Table 2 Demography, pre-treatment clinical and CADIA sites profiles of participants

Age

mean ± SD

43.6 ± 7.6

49.0 ± 5.0

t

2.0317

0.0539

Smoking habit (self-reported)

Baseline

Smoked years

22.4 ± 7.7

25.0 ± 8.1

t

0.8193

0.4210

Cigarettes/day

20.0 ± 9.2

22.3 ± 8.2

t

0.6502

0.5220

Pack-years

22.2 ± 11.0

30.2 ± 21.4

t

1.2140

0.2371

End of study

Cigarettes/day

18.6 ± 7.6

21.4 ± 7.8

t

0.9040

0.3754

Full-mouth parameter

Standing teeth

mean ± SD

23.1 ± 3.5

21.4 ± 3.2

t

1.272

0.2166

Plaque  %

mean ± SD

89.4 ± 4.4

88.3 ± 7.1

t

0.3991

0.6954

BOP %

mean ± SD

83.7 ± 11.9

86.8 ± 13.2

t

0.6085

0.5497

% PPD ≥ 5 mm

mean ± SD

42.7 ± 19.4

44.6 ± 20.1

t

0.2382

0.8140

% PAL ≥ 7 mm

mean ± SD

80.6 ± 13.1

73.3 ± 21.0

t

1.009

0.3290

CADIA sites (2/participant)

Tooth type

Incisor

8/0 (8)^a

6/1 (7)

χ²

2.487

0.2884

Canine

7/5 (12)

3/2 (5)

Premolar

4/4 (8)

5/5 (10)

Plaque  %

100

100

BOP %

90.8

96.1

χ²

1.255

0.2626

PPD

mean ± SD

6.17 ± 1.68

6.33 ± 1.23

t

0.592

0.5598

PAL

mean ± SD

9.86 ± 2.23

9.02 ± 1.53

t

1.066

0.2977