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Table 1 Viability percentage of MDA-MB-231 at 48 h treated with bromelain and cisplatin combinations

From: Combination of cisplatin and bromelain exerts synergistic cytotoxic effects against breast cancer cell line MDA-MB-231 in vitro

Combination no.

Combination dosage (µM)

% viability ± SD

Bromelain dosage (IC value)

Cisplatin dosage (IC value)

Combination 1

2.0 µM (IC40)

1.5 µM (IC10)

50.24% ± 1.67

Combination 2

0.9 µM (IC30)

4.0 µM (IC20)

70.26% ± 2.66

Combination 3

0.5 µM (IC20)

5.9 µM (IC30)

61.30% ± 2.43

Combination 4

0.24 µM (IC10)

9.5 µM (IC40)

56.95% ± 3.61

  1. Cytotoxicity was determined using the MTT cell viability assay. The results for MTT assay are expressed as mean ± SD of three separate experiments
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Chinese Medicine

ISSN: 1749-8546

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