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Table 2 Effects of BTS on mRNA expression of leptin, adiponectin, UCP1, and UCP2 in interscapular brown adipose tissue and epididymal white adipose tissues after 5 days’ administration

From: Mechanisms for the anti-obesity actions of bofutsushosan in high-fat diet-fed obese mice

  −BTS +BTS P value
Interscapular brown adipose tissue
 Leptin 0.0264 ± 0.0080 0.1182 ± 0.0612 0.0004
 Adiponectin 0.7679 ± 0.2436 2.5412 ± 2.1369 0.0250
 UCP1 2.2519 ± 0.9376 3.3746 ± 0.6704 0.0100
 UCP2 0.0717 ± 0.0210 0.0833 ± 0.0430 0.4781
Epididymal white adipose tissue
 Leptin 0.0512 ± 0.0243 0.0390 ± 0.0203 0.3756
 Adiponectin 0.6115 ± 0.5319 0.9395 ± 0.4682 0.1839
 UCP1 0.0015 ± 0.0008 0.0020 ± 0.0014 0.5207
 UCP2 0.1560 ± 0.0252 0.1777 ± 0.0930 0.5347
  1. Relative quantification of mRNA expression by real-time PCR was calculated relative to β-actin mRNA. Values are expressed as mean ± SD (n = 4–9). P values were calculated by Student’s t test. P < 0.05, BTS group is considered significantly different from control group without BTS