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Table 3 Functional enrichments in protein network

From: Effect of methanol extract of Salviae miltiorrhizae Radix in high-fat diet-induced hyperlipidemic mice

Pathway ID Pathway description Count in gene set False discovery rate
Biological process (GO)
 GO:0006270 DNA replication initiation 4 0.00262
 GO:0006268 DNA unwinding involved in DNA replication 3 0.0227
Molecular function (GO)
 GO:0003678 DNA helicase activity 4 0.00299
 GO:0004386 Helicase activity 6 0.00299
 GO:0032559 Adenyl ribonucleotide binding 16 0.00299
 GO:0036094 Small molecule binding 21 0.00299
 GO:0000166 Nucleotide binding 19 0.00685
 GO:0004691 cAMP-dependent protein kinase activity 2 0.00951
 GO:0004748 Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor 2 0.00951
 GO:0097367 Carbohydrate derivative binding 18 0.00951
 GO:0005524 ATP binding 14 0.0139
 GO:0043168 Anion binding 19 0.0149
 GO:0051018 Protein kinase A binding 3 0.023
Cellular component (GO)
 GO:0042555 MCM complex 6 2.29e−10
 GO:0005952 cAMP-dependent protein kinase complex 3 0.00123
 GO:0097362 MCM8-MCM9 complex 2 0.00495
 GO:0070033 Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex 2 0.0111
 GO:0070032 Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex 2 0.0178
  1. GO terms and pathways associated with differentially expressed genes of liver tissues in hyperlipidemic mice. False discovery rate corrections were calculated using the Benjamini–Hochberg procedure