Fig. 1

Design of the MCAO model. The mice were pretreated with methanol extract of Peucedani Radix (PRex) for three consecutive days before MCAO and the mice were killed 24 h after MCAO. During the ischemic conditioning, the relative cerebral blood flow (rCBF) was monitored by using Laser-Doppler flowmetry. LCCA left common carotid artery, MCA middle cerebral artery