Fig. 3

Effects of PRex pretreatment on infarct volumes (a) and neuronal deficit score (b) in the brains of MCAO-injured mice. The PRex pretreatment significantly decreased the infarct volumes at 24 h after MCAO. But pretreatment of PRex did not improve neuronal deficit scores. The results are presented as the mean ± SD. ^###p < 0.001 vs sham control group, **p < 0.01, ***p < 0.001 vs MCAO control group; n = 8 in each group