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Fig. 5 | Chinese Medicine

Fig. 5

From: Active fraction (HS7) from Taiwanofungus camphoratus inhibits AKT-mTOR, ERK and STAT3 pathways and induces CDK inhibitors in CL1-0 human lung cancer cells

Fig. 5

Inhibitory effects of HS7 on the AKT-mTOR signaling pathway and its downstream effectors in CL1-0 lung cancer cells after 72 h of treatment. a HS7 decreased the protein levels of phosphorylated AKT (p-AKT) and phosphorylated mTOR (p-mTOR) in a dose-dependent manner. b HS7 dose-dependently decreased the phosphorylated p70S6K protein (p-p70S6K). c HS7 dose-dependently decreased the HIF-1α protein. Cell lysates were analyzed by Western blot, using tubulin as loading control

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