Fig. 5

Percentage of female rats with vaginal opening occurring between PND 28 and 43. One rat in the Huang Bai 300 mg/kg group and all rats in the triptorelin group failed to show vaginal opening. Control: DW (p.o.), HB100: Huang Bai (100 mg/kg, p.o.), HB300: Huang Bai (300 mg/kg, p.o.), rhGH: recombinant human growth hormone (20 μg/kg, s.c.), estradiol: 17β-estradiol (1 μg/kg, s.c.), triptorelin: triptorelin (100 μg, i.p.)