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Table 2 Absorption parameters of triptolide in perfusate solution within duodenum, jejunum, ileum and colon (\( {\bar{\text{x}}} \pm {\text{s}} \), n = 6)

From: Different modulation of Panax notoginseng on the absorption profiling of triptolide and tripterine from Tripterygium wilfordii in rat intestine

Parameters

Con. (μg/mL)

Duodenum

Jejunum

Ileum

Colon

Peff × 10−3

3

5.20 ± 1.72

4.98 ± 1.67

6.46 ± 2.0

6.35 ± 1.28

6

5.05 ± 1.91

4.85 ± 1.88

6.36 ± 1.92

6.20 ± 1.45

9

5.14 ± 0.56

4.77 ± 2.21

6.29 ± 2.31

6.36 ± 1.17

10 cm%ABS

3

42.7 ± 1.85

41.3 ± 2.4

47.8 ± 1.64

41.1 ± 3.33

6

46.5 ± 3.52

41.6 ± 1.28

47.8 ± 1.34

41.8 ± 2.87

9

45.8 ± 4.03

41.4 ± 1.67

48.4 ± 1.69

41.9 ± 2.88

Ka × 10−2

3

1.79 ± 0.33

1.64 ± 0.39

2.93 ± 0.29

1.81 ± 0.11

6

1.75 ± 0.29

1.49 ± 0.79

2.86 ± 0.34

1.77 ± 0.23

9

1.69 ± 0.31

1.53 ± 0.84

2.93 ± 0.24

1.69 ± 0.29