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Table 2 Absorption parameters of triptolide in perfusate solution within duodenum, jejunum, ileum and colon (\( {\bar{\text{x}}} \pm {\text{s}} \), n = 6)

From: Different modulation of Panax notoginseng on the absorption profiling of triptolide and tripterine from Tripterygium wilfordii in rat intestine

Parameters Con. (μg/mL) Duodenum Jejunum Ileum Colon
Peff × 10−3 3 5.20 ± 1.72 4.98 ± 1.67 6.46 ± 2.0 6.35 ± 1.28
6 5.05 ± 1.91 4.85 ± 1.88 6.36 ± 1.92 6.20 ± 1.45
9 5.14 ± 0.56 4.77 ± 2.21 6.29 ± 2.31 6.36 ± 1.17
10 cm%ABS 3 42.7 ± 1.85 41.3 ± 2.4 47.8 ± 1.64 41.1 ± 3.33
6 46.5 ± 3.52 41.6 ± 1.28 47.8 ± 1.34 41.8 ± 2.87
9 45.8 ± 4.03 41.4 ± 1.67 48.4 ± 1.69 41.9 ± 2.88
Ka × 10−2 3 1.79 ± 0.33 1.64 ± 0.39 2.93 ± 0.29 1.81 ± 0.11
6 1.75 ± 0.29 1.49 ± 0.79 2.86 ± 0.34 1.77 ± 0.23
9 1.69 ± 0.31 1.53 ± 0.84 2.93 ± 0.24 1.69 ± 0.29