Fig. 1

Decoction of Hedyotis diffusa (HD) relieves the acute inflammation in hepatitis mouse. a Administration of HD decoction blocked LPS/GALN-induced up-regulation of mRNA levels of CXCL1, TNF-α, IL-1β, MIP-2. b The treatment of HD decoction reduced the expressed levels of TNF-α, IL-1β, IL-6 and MCP-1 in liver of LPS/GALN-injected mice. c Alanine transaminase (ALT) level was measured in control or LPS/GALN- and LPS/GALN + HD-treated mouse. HD decoction significantly reduced the level of ALT (n = 5). d Aspartate transaminase (AST) level was measured in control or LPS/GALN- and LPS/GALN + HD-treated mouse. HD decoction significantly reduced the level of AST (n = 5). e Survival of hepatitis mouse was measured after treatment of HD decoction (n = 20, per group) within 20 days. f Effect of HD on LPS/GALN-mediated liver histopathologic changes