Fig. 5
From: Metabolic regulations of a decoction of Hedyotis diffusa in acute liver injury of mouse models
Investigation of vital metabolites that separate LPS/GALN + HD from the LPS/GALN using independent component analysis (ICA). a ICA directly represents variation of metabolites among control, LPS/GALN and LPS/GALN + HD. Each dot in the plot represents the replicate analysis of samples. b The weight distribution on IC01 and IC02 for the metabolites are shown. The weight (also called loadings) are proportional to the importance or significance of a metabolite for a corresponding independent component, in other words, the observed biological phenomenon. The interpretations of IC01 and IC02 correspond to a. Blue box indicates the metabolites which have largest the loadings. c Comparison of cholesterol, tryptophan, and lactic acid among control, LPS/GALN and LPS/GALN + HD. Error bars ± SD, **P < 0.01