TY - JOUR AU - Zhang, Qing-Wen AU - Lin, Li-Gen AU - Ye, Wen-Cai PY - 2018 DA - 2018/04/17 TI - Techniques for extraction and isolation of natural products: a comprehensive review JO - Chinese Medicine SP - 20 VL - 13 IS - 1 AB - Natural medicines were the only option for the prevention and treatment of human diseases for thousands of years. Natural products are important sources for drug development. The amounts of bioactive natural products in natural medicines are always fairly low. Today, it is very crucial to develop effective and selective methods for the extraction and isolation of those bioactive natural products. This paper intends to provide a comprehensive view of a variety of methods used in the extraction and isolation of natural products. This paper also presents the advantage, disadvantage and practical examples of conventional and modern techniques involved in natural products research. SN - 1749-8546 UR - https://doi.org/10.1186/s13020-018-0177-x DO - 10.1186/s13020-018-0177-x ID - Zhang2018 ER -