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Fig. 4 | Chinese Medicine

Fig. 4

From: Cellular stress response mechanisms of Rhizoma coptidis: a systematic review

Fig. 4

Molecular mechanisms of Rhizoma coptidis on AMPK pathways (—• indicates inhibition/reduction, arrow indicates promotion/stimulation). Rhizoma coptidis can activate AMPK pathways via modulating upstream targets (i.e., LKB1). Once AMPK is activated, downstream signals of AMPK will be stimulated to demonstrate multiple biological effects, including anti-obesity, anti-diabetes, etc.

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