Fig. 6
From: Cellular stress response mechanisms of Rhizoma coptidis: a systematic review
Molecular mechanisms of Rhizoma coptidis on ERS pathways (—• indicates inhibition/reduction, arrow indicates promotion/stimulation). ERS pathways can be inhibited by Rhizoma coptidis at least two ways, including inhibition of the expression of IRE-1 and inhibition of the phosphorylation of PERK