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Fig. 3 | Chinese Medicine

Fig. 3

From: Siegesbeckia pubescens Makino inhibits Pam3CSK4-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-κB activation

Fig. 3

Siegesbeckia pubescens Makino (SP) exhibited anti-inflammatory effects in Pam3CSK4-stimulated RAW 264.7 cells (n = 3). RAW 264.7 cells were pretreated with SP with different concentrations for 4 h before Pam3CSK4 (200 ng/mL) stimulation for another 12 h. a Nitric oxide (NO) was determined by Griess assay. TLR1/TLR2 antagonist: CU-CPT22 (CU) was selected as the positive control. We measured the levels of b IL-6, c TNF-α, and d MCP-1 by ELISA assay. *P < 0.05 vs. Pam3CSK4-induced, **P < 0.01 vs. Pam3CSK4-induced, ***P < 0.001 vs. Pam3CSK4-induced

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Chinese Medicine

ISSN: 1749-8546

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