Fig. 7

GO functional analysis. a Biological processes terms were extrinsic apoptotic signaling pathway, positive regulation of reactive oxygen species metabolic process, protein kinase B signaling, positive regulation of sequence-specific DNA binding transcription factor activity, and response to corticosteroids etc. b Cell component terms included plasma membrane raft, nuclear transcription factor complex, caveola RNA polymerase II transcription factor complex, platelet alpha granule, platelet alpha granule lumen etc. c Molecular function terms were growth factor receptor binding, cytokine activity, ion channel regulator activity, nitric-oxide synthase regulator activity, steroid binding etc. d Significant KEGG pathways were AGE-RAGE in diabetic complications, fluid shear stress, atherosclerosis, PI3K-Akt, MAPK, and FoxO signaling pathway etc