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Table 1 Effects of HM, GQD and FGQD on FINS, ISI and HOMA-IR of T2DM rats

From: Comparing the antidiabetic effects and chemical profiles of raw and fermented Chinese Ge-Gen-Qin-Lian decoction by integrating untargeted metabolomics and targeted analysis

Group FINS (mIU/L) ISI HOMA-IR
NC 4.92 ± 0.74 − 3.38 ± 0.24 1.33 ± 0.30
DM 9.88 ± 0.58** − 5.24 ± 0.22** 8.59 ± 1.75**
HM 7.17 ± 0.54## − 4.47 ± 0.36## 3.98 ± 1.07##
GQD 6.78 ± 0.35 − 4.52 ± 0.23 4.18 ± 0.95
FGQD 5.86 ± 0.55▲▲ − 4.26 ± 0.18 3.20 ± 0.60
  1. NC normal control, DM diabetic model, HM metformin hydrochloride, ISI insulin sensitivity index, FINS fast serum insulin, HOMA-IR homeostasis model assessment-insulin resistance, T2DM type 2 diabetes mellitus
  2. **p < 0.01 DM vs NC; #p < 0.05, ##p < 0.01 HM vs DM; p < 0.01 GQD vs DM; p < 0.01 FGQD vs DM; ▲▲p < 0.01 FGQD vs GQD