Fig. 3

The paraffin-embedded sections of the lungs and livers were photographed and used to measure metastatic loci area and total lung or liver area. a Representative photographs of lungs and livers were shown. Arrows indicated the tumor nodules. The histograms showed the tumor burden in b lungs and c livers according to the tumor area as a percentage of whole lung or liver area per group (n = 12). d Effects of formula treatments on bone volume of tumor-bearing mice. Quantitative assessment of bone structure in mouse tibias after formula or doxorubicin treatments. The graph showed the bone volume of tibias from different groups (n = 10). Data were expressed as mean + SEM. Differences among the treated and control groups were determined by one-way ANOVA followed by Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01, ***p < 0.005 as compared to control group. ^#p < 0.05 when compared among treatment groups