Table 3 Natural anti-biofilm agents under clinical evaluation (http://clinicaltrials.gov/)
From: Developing natural products as potential anti-biofilm agents
Condition | Status | Intervention | Phase | Year |
|---|---|---|---|---|
Biofilms Essential oils Periodontitis | Not yet recruiting | Drug: Essential oils Drug: Essential oils without alcohol Drug: Sterile water | IV | 2016 |
Biofilms Substantivity Essential oils | Not yet recruiting | Drug: Essential oils Drug: Essential oils without mouthwash Drug: Sterile water | IV | 2016 |
Oral biofilm Dental plaque Periodontitis | Recruiting | Drug: Essential oils Drug: Alcohol free essential oils Other: Water | IV | 2017 |
Streptococcal infections Saliva altered | Completed | Other: Propolis varnish | I and II | 2015 |
Gingivitis | Completed | Dietary supplement: Black tea Dietary supplement: Green tea Drug: 0.12% chlorhexidine mouthwash | III | 2015 |
Oral biofilm Mouthwash Periodontitis | Completed | Drug: Essential oils Drug: 0.2% chlorhexidine Drug: Sterile water | IV | 2013 |
Dental biofilm pH | Completed | Other: G1, G2 and G3 Other: G4 and G5 | II | 2012 |
Gingivitis | Completed | Drug: Punica granatum Linn. Drug: chlorhexidine | Not applicable | 2012 |
Prostheses-related infections | Completed | Other: Physiological solution Other: Sodium hypochlorite Other: Alkaline peroxide Other: Castor bean solution | Not applicable | 2011 |