Skip to main content

Table 2 Cytotoxicities of selected compounds (IC50 μM)

From: A pair of new enantiomers of xanthones from the stems and leaves of Cratoxylum cochinchinense

Compounds HL-60 PC-3 MDA-MB-231
1a 12.08 ± 0.84 > 50 > 50
1b 19.24 ± 1.51 > 50 18.46 ± 1.65
3 19.78 ± 2.09 > 50 > 50
4 18.00 ± 1.04 > 50 > 50
6 15.56 ± 0.51 > 50 > 50
9 > 50 > 50 > 50
10 10.43 ± 0.31 > 50 > 50
11 > 50 > 50 > 50
12 10.77 ± 0.13 > 50 > 50
19 2.62 ± 0.74 21.87 ± 1.94 7.94 ± 0.94
20 4.50 ± 0.17 11.77 ± 0.19 11.97 ± 0.65
21 3.07 ± 0.16 27.11 ± 1.49 13.30 ± 1.09
22 9.64 ± 0.34 20.60 ± 1.64 14.59 ± 1.26
23 1.00 ± 0.21 11.95 ± 1.36 9.40 ± 1.28
24 6.18 ± 0.31 14.99 ± 1.28 15.96 ± 0.46
25 4.47 ± 0.14 14.57 ± 1.27 11.55 ± 1.25
27 1.89 ± 0.54 22.94 ± 1.97 > 50
28 4.52 ± 0.97 20.72 ± 2.04 16.37 ± 1.32
5-FU a 2.20 ± 0.08 25.98 ± 1.08 38.69 ± 2.84
  1. IC50 values expressed as mean ± standard deviation, n = 3
  2. aPositive control