Table 2 Cytotoxicities of selected compounds (IC50 μM)
From: A pair of new enantiomers of xanthones from the stems and leaves of Cratoxylum cochinchinense
Compounds | HL-60 | PC-3 | MDA-MB-231 |
|---|---|---|---|
1a | 12.08 ± 0.84 | > 50 | > 50 |
1b | 19.24 ± 1.51 | > 50 | 18.46 ± 1.65 |
3 | 19.78 ± 2.09 | > 50 | > 50 |
4 | 18.00 ± 1.04 | > 50 | > 50 |
6 | 15.56 ± 0.51 | > 50 | > 50 |
9 | > 50 | > 50 | > 50 |
10 | 10.43 ± 0.31 | > 50 | > 50 |
11 | > 50 | > 50 | > 50 |
12 | 10.77 ± 0.13 | > 50 | > 50 |
19 | 2.62 ± 0.74 | 21.87 ± 1.94 | 7.94 ± 0.94 |
20 | 4.50 ± 0.17 | 11.77 ± 0.19 | 11.97 ± 0.65 |
21 | 3.07 ± 0.16 | 27.11 ± 1.49 | 13.30 ± 1.09 |
22 | 9.64 ± 0.34 | 20.60 ± 1.64 | 14.59 ± 1.26 |
23 | 1.00 ± 0.21 | 11.95 ± 1.36 | 9.40 ± 1.28 |
24 | 6.18 ± 0.31 | 14.99 ± 1.28 | 15.96 ± 0.46 |
25 | 4.47 ± 0.14 | 14.57 ± 1.27 | 11.55 ± 1.25 |
27 | 1.89 ± 0.54 | 22.94 ± 1.97 | > 50 |
28 | 4.52 ± 0.97 | 20.72 ± 2.04 | 16.37 ± 1.32 |
5-FU a | 2.20 ± 0.08 | 25.98 ± 1.08 | 38.69 ± 2.84 |