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Table 3 Results of AUCs for biomarkers

From: Combination of 15 lipid metabolites and motilin to diagnose spleen-deficiency FD

Biomarkers and laboratory data

Spleen deficiency-FD vs. HC

AUC

P-value

95% CI

Top biomarkers

 LysoPC (18:0)

0.8053

< 0.0001

–

 PC (22:6/0:0)

0.9039

< 0.0001

–

 LysoPC (17:0)

0.6790

0.0002

–

 LysoPC (18:1)

0.9895

< 0.0001

–

 LysoPC (20:4)

0.9793

< 0.0001

–

 PC (17:2/0:0)

0.8891

< 0.0001

–

 PC (17:1/0:0)

0.9926

< 0.0001

–

 LysoPC (16:1)

0.9441

< 0.0001

–

 LysoPE (18:2/0:0)

0.9438

< 0.0001

–

 PC (15:0/0:0)

0.9655

< 0.0001

–

 PC (16:0/0–1:0)

0.9267

< 0.0001

–

 LysoPE (0:0/16:0)

0.7155

< 0.0001

–

 LysoPE (20:4/0:0)

0.9633

< 0.0001

–

 LysoPE (0:0/22:6)

0.9743

< 0.0001

–

 LysoPC (20:3)

0.9136

< 0.0001

–

Laboratory data

 Motilin

0.8487

< 0.0001

–

The combination of top biomarkers

0.9943

< 0.0001

0.9845–1.000

The combination of top biomarkers and motilin

0.9615

< 0.0001

0.9264–0.9967