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Table 2 Comparison with the working concentration of components from Danshen in anti-Aβ-induced cytotoxicity and anti-Aβ aggregation

From: The effects of bioactive components from the rhizome of Salvia miltiorrhiza (Danshen) on the characteristics of Alzheimer’s disease

Compounds from Danshen The effective concentration against Aβ-induced cytotoxicity The effective concentration on Aβ aggregation
Salvianolic acid A 5, 10, 20, and 40 μM in SH-SY5Y cells [47] 1, 4, 10, and 40 μM [47]
Salvianolic acid B 10, 100, and 200 μg/ml in PC12 cells [53]
50 μM in mouse neurons [52]
Danshensu 10, 100, and 200 μg/ml in PC12 cells [53]
Tanshinone I 4 μM in SH-SY5Y cells [64] 20 and 40 μM [64]
Tanshinone IIA 4 μM in SH-SY5Y cells [64]
1, 5, 10, 20 μM in SH-SY5Y cells [68]
20 and 40 μM [64]
10, 20, and 40 μM in mouse cortical neurons [66]
0.1, 1, and 10 μM in rat cortical neurons [67]
Cryptotanshinione 5 and 10 μM in SH-SY5Y cells [74] 1, 2.5, and 5 μM [74]