Skip to main content

Table 2 Comparison with the working concentration of components from Danshen in anti-Aβ-induced cytotoxicity and anti-Aβ aggregation

From: The effects of bioactive components from the rhizome of Salvia miltiorrhiza (Danshen) on the characteristics of Alzheimer’s disease

Compounds from Danshen

The effective concentration against Aβ-induced cytotoxicity

The effective concentration on Aβ aggregation

Salvianolic acid A

5, 10, 20, and 40 μM in SH-SY5Y cells [47]

1, 4, 10, and 40 μM [47]

Salvianolic acid B

10, 100, and 200 μg/ml in PC12 cells [53]

50 μM in mouse neurons [52]

Danshensu

10, 100, and 200 μg/ml in PC12 cells [53]

Tanshinone I

4 μM in SH-SY5Y cells [64]

20 and 40 μM [64]

Tanshinone IIA

4 μM in SH-SY5Y cells [64]

1, 5, 10, 20 μM in SH-SY5Y cells [68]

20 and 40 μM [64]

10, 20, and 40 μM in mouse cortical neurons [66]

0.1, 1, and 10 μM in rat cortical neurons [67]

Cryptotanshinione

5 and 10 μM in SH-SY5Y cells [74]

1, 2.5, and 5 μM [74]