Fig. 2From: A tannin compound from Sanguisorba officinalis blocks Wnt/β-catenin signaling pathway and induces apoptosis of colorectal cancer cellsThe effect on the Wnt signaling pathway in NIH3T3 cells treated with Wnt3a. a The influences on β-catenin in different parts of NIH3T3 cells by Immunofluorescence assays. The level of β-catenin in nucleus was up-regulated which was indicated by the arrow. b The luciferase reporter assay showed that the Wnt signal was activated in NIH3T3 cells treated with Wnt3a. c The expression level of β-catenin was up-regulated in NIH3T3 cells treated with Wnt3a by western blotBack to article page