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Fig. 4 | Chinese Medicine

Fig. 4

From: A tannin compound from Sanguisorba officinalis blocks Wnt/β-catenin signaling pathway and induces apoptosis of colorectal cancer cells

Fig. 4

Effects of DY, DY-B, DYB4 on the β-catenin and Wnt target genes in colorectal cancer cell (HT29). a–c Respectively suggest that DY (40 μg/mL), DY-B (40 μg/mL) down- regulated the expression of β-catenin and Wnt target genes (Axin2, Dkk1, c-Myc, FGF20, NKD-1, Survivin), DYB4 (40 μM) also down-regulated the level of β-catenin and the mRNA of Dkk1, c-Myc, FGF20, Survivin. *P < 0.05, **P < 0.01, ***P < 0.001, vs. control group

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Chinese Medicine

ISSN: 1749-8546

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