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Table 4 The stability of the six components in rat plasma samples

From: Simultaneous UPLC–TQ-MS/MS determination of six active components in rat plasma: application in the pharmacokinetic study of Cyclocarya paliurus leaves

Analytes Nominal concentration (ng/ml) Frozen for 15 days at − 20 °C Three-free-thaw cycles Auto-sampler for 24 h
Precision (RSD, %) Accuracy (RE, %) Precision (RSD, %) Accuracy (RE, %) Precision (RSD, %) Accuracy (RE, %)
Neochlorogenic acid 120 12.24 12.06 14.24 − 12.82 11.20 − 11.03
  1200 9.39 − 10.45 10.39 − 12.41 6.35 10.03
  12,000 9.36 7.35 10.36 5.35 9.33 13.02
Chlorogenic acid 120 12.03 − 9.60 14.03 − 15.01 13.36 12.53
  1200 10.02 8.03 11.63 14.06 12.59 − 9.36
  12,000 6.50 − 8.59 14.30 14.03 9.36 8.03
Quercetin-3-O-glucuronide 40 13.02 − 11.20 13.63 5.16 7.26 − 12.25
  400 8.20 14.06 10.96 − 11.52 5.88 4.62
  4000 9.56 10.12 15.05 8.29 9.26 − 9.13
Kaempferol-3-O-rhamnoside 5 14.01 12.58 9.86 − 9.86 3.89 − 9.59
  50 14.23 12.63 8.16 − 11.05 12.50 9.25
  500 15.20 15.03 12.03 7.16 6.23 − 6.33
Quercetin 1.5 10.36 − 12.3 7.59 7.68 9.51 14.59
  15 12.60 − 10.52 8.16 11.20 5.62 6.09
  150 10.24 9.35 12.14 − 15.01 8.45 11.13
Kaempferol 20 14.05 9.18 9.68 14.10 9.66 − 15.01
  200 10.02 − 11.05 15.11 − 15.02 7.33 11.06
  2000 9.05 11.56 9.13 11.30 6.03 11.42