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Table 4 Down-regulated proteins with a fold change ≤ 0.67 under GZZSZTW treatment (GZZSZTW vs. Blank)

From: Dissection of the molecular targets and signaling pathways of Guzhi Zengsheng Zhitongwan based on the analysis of serum proteomics

Protein name

Fold change

p value

Kininogen-1 (KNG1)

0.22

0.02

Coiled-coil domain-containing protein 85C (CCDC85C)

0.22

0.02

Pyrethroid hydrolase Ces2a (CES2A)

0.27

0

Zinc finger homeobox protein 2 (ZFHX2)

0.28

0

Probable hydrolase PNKD (PNKD)

0.29

0.04

Apolipoprotein F (APOF)

0.29

0

Alpha-1B-glycoprotein (A1BG)

0.42

0

Serine protease hepsin (HPN)

0.43

0

Alcohol dehydrogenase 1 (ADH1)

0.44

0

Serine protease inhibitor A3N (SERPINA3N)

0.48

0

NF-kappa-B inhibitor zeta (NFKBIZ)

0.48

0

Thyrotropin-releasing hormone-degrading ectoenzyme (TRHDE)

0.48

0.02

Beta-2-glycoprotein 1 (APOH)

0.52

0

Glucosidase 2 subunit beta (PRKCSH)

0.52

0

Alpha-1-antiproteinase (SERPINA1)

0.55

0

Proprotein convertase subtilisin/kexin type 9 (PCSK9)

0.56

0

CD5 antigen-like (CD5L)

0.58

0

Apolipoprotein B-100 (APOB)

0.58

0

Angiopoietin-related protein 3 (ANGPTL3)

0.60

0

Ficolin-2 (FCN2)

0.60

0

T-kininogen 1 (MAP1)

0.61

0

Osteomodulin (OMD)

0.65

0

Keratinocyte differentiation-associated protein (KRTDAP)

0.66

0

Hyaluronan-binding protein 2 (HABP2)

0.66

0

Translationally-controlled tumor protein (TPT1)

0.66

0.02

Napsin-A (NAPSA)

0.66

0