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Table 1 Effects of BZD, ZD and BD on the immobility time of ICR mice in FST and TST

From: Identifying the active components of Baihe–Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests

Groups

Dosage

Immobility time (mean ± SD, s)

FST

TST

Control

–

127.6 ± 40.9

109.1 ± 15.5

Fluoxetine

10 mg/kg

84.8 ± 15.2*

62.0 ± 36.2**

BZD

3 g/kg

90.1 ± 26.4*

67.3 ± 35.8**

ZD

3 g/kg

85.9 ± 28.2*

83.0 ± 23.0*

BD

3 g/kg

92.4 ± 38.2

95.6 ± 15.9

  1. BZD, ZD and BD represented Baihe–Zhimu decoction, Zhimu decoction and Baihe decoction, respectively
  2. FST and TST represented forced swimming test and tail suspension test, respectively
  3. * P < 0.05 and ** P < 0.01 compared with control group
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Chinese Medicine

ISSN: 1749-8546

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