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Table 1 Effects of BZD, ZD and BD on the immobility time of ICR mice in FST and TST

From: Identifying the active components of Baihe–Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests

Groups Dosage Immobility time (mean ± SD, s)
FST TST
Control 127.6 ± 40.9 109.1 ± 15.5
Fluoxetine 10 mg/kg 84.8 ± 15.2* 62.0 ± 36.2**
BZD 3 g/kg 90.1 ± 26.4* 67.3 ± 35.8**
ZD 3 g/kg 85.9 ± 28.2* 83.0 ± 23.0*
BD 3 g/kg 92.4 ± 38.2 95.6 ± 15.9
  1. BZD, ZD and BD represented Baihe–Zhimu decoction, Zhimu decoction and Baihe decoction, respectively
  2. FST and TST represented forced swimming test and tail suspension test, respectively
  3. * P < 0.05 and ** P < 0.01 compared with control group