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Table 4 Effects of timosaponin BII and timosaponin BIII on the immobility time of ICR mice in FST and TST

From: Identifying the active components of Baihe–Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests

Groups Dosage (mg/kg) Immobility time (mean ± SD, s)
FST TST
Control 118.1 ± 24.3 102.0 ± 16.9
Fluoxetine 10 70.2 ± 21.2* 50.0 ± 22.2*
Timosaponin B-II 10 72.1 ± 19.6* 48.2 ± 23.1*
Timosaponin B-III 10 68.6 ± 23.2* 58.4 ± 15.6*
  1. FST and TST represented forced swimming test and tail suspension test, respectively
  2. * P < 0.05 compared with control group