Table 5 The accuracy (intra- and inter-day) (n = 5), precision (n = 5), extract recovery (n = 5) and stability (n = 3) for 3 components in rabbits plasma
From: Preparation, optimization and in vitro–in vivo evaluation of Shunxin sustained release granules
Components | Concentration (μg/mL) | Accuracy (RSD%) | Precision (%) | Extract recovery (%) | Stability (RSD%) | ||
|---|---|---|---|---|---|---|---|
Inter-day | Intra-day | At − 20 °C 7 days | Freeze–thaw cycles | ||||
Paeoniflorin | Low | 5.68 | 4.13 | 102.03 | 89.68 | 5.52 | 6.15 |
Medium | 2.47 | 2.78 | 103.47 | 94.07 | 3.37 | 6.90 | |
High | 3.36 | 6.31 | 98.79 | 95.99 | 4.17 | 8.25 | |
Calycosin-7-glucoside | Low | 4.84 | 7.25 | 105.68 | 86.90 | 5.28 | 7.90 |
Medium | 4.08 | 5.57 | 88.53 | 89.91 | 5.57 | 6.53 | |
High | 6.33 | 7.44 | 98.33 | 91.33 | 5.69 | 7.14 | |
Ferulic acid | Low | 2.38 | 7.84 | 86.56 | 79.90 | 3.24 | 8.09 |
Medium | 3.10 | 2.24 | 96.05 | 82.08 | 4.24 | 6.87 | |
High | 5.68 | 8.76 | 97.26 | 84.66 | 7.09 | 8.40 | |