Fig. 5

Expression of seven cytokines changed significantly from liver-gallbladder dampness-heat syndrome (LGDHS) to liver-kidney yin-deficiency syndrome (LKYDS). a–g Cytokine expression of CCL3, IL17, IL15, CCL27, LIF, CLEC11A, and CSF2. These cytokines were significantly expressed between LGHDS and LKYDS. The vertical axis represents absolute quantification of cytokines measured by enzyme-linked immunosorbent assay (ELISA). h, i Validation of DNBs plasminogen (PLG) and coagulation factor XII (F12) in the proteomic data. The vertical axis represents signal ratio compared to the healthy group. a–i The p values were measured by Mann–Whitney U tests