Table 1 Quantitative analysis on the chemical markers in the DAEP herbal paste and their transdermal property
From: Topical application of Chinese herbal medicine DAEP relieves the osteoarthritic knee pain in rats
Chemical marker | Herb | Conc. in paste (%) | Conc. in porcine skin (μg) | Conc. in receiving chamber (μg) | Molecular weight (g/mol) | Topological polar surface area (A2) |
|---|---|---|---|---|---|---|
Ginsenoside Ro | ABR | 0.15 | 6.64 | 0.00 | 957.12 | 312.0 |
Chikusetsusaponin IV A | ABR | 0.01 | 12.39 | 0.00 | 927.09 | 292.0 |
Asperosaponin VI | DR | 1.77 | 393.48 | 5.09 | 929.11 | 295.0 |
Pinoresinol diglucoside | EC | 0.23 | 80.38 | 8.42 | 682.67 | 236.0 |
β-ecdysterone | ABR | 0.02 | 4.82 | 0.51 | 480.64 | 138.0 |
Psoralen | PF | 0.37 | 54.41 | 9.25 | 186.17 | 39.4 |
Isopsoralen | PF | 0.33 | 45.11 | 9.51 | 186.17 | 39.4 |