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Fig. 5 | Chinese Medicine

Fig. 5

From: Effect of Loureirin B on Crohn’s disease rat model induced by TNBS via IL-6/STAT3/NF-κB signaling pathway

Fig. 5

Effect of LB on epithelial-mesenchymal transition (EMT) in rats induced with TNBS. a Masson’s trichrome staining assay was performed to investigate the fibrotic changes histopathologically of colonic tissues of CD rats from different groups. b Western blotting assay was carried out to examine the expression levels of EMT-related proteins, including Slug, Snail, N-cadherin, E-cadherin and Vimentin of colonic tissues of CD rats from different groups. The band intensity was quantified by Image J software. F = 0.7712, df = 29. c Immunohistochemistry assay was performed to evaluate the expression levels of EMT-related proteins in colonic tissues of CD rats from different groups. F = 1.989, df = 29. The results were expressed as the mean ± SD of at least three experiments. ##P < 0.01 compared with the control group. *P < 0.05, **P < 0.01 compared with the model group

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Chinese Medicine

ISSN: 1749-8546

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