Fig. 7

Effect of LB on IL-6/STAT3/NF-κB signaling pathway in rats induced with TNBS. a The functional activity of NF-κB was accessed by EMSA. b, c qRT-PCR and western blot assays were performed to evaluate the mRNA and protein expression of IL-6/STAT3/NF-κB signaling pathway of colonic tissues of CD rats from different groups. The band intensity was quantified by Image J software. The results were expressed as the mean ± SD of at least three experiments. ^##P < 0.01 compared with the control group. *P < 0.05, **P < 0.01 compared with the model group