Fig. 1

Effects of EOFAZ on metabolic parameters and retina histology in diabetes rats. Rats were daily fed with HFSD for 3 months. Detection of TGs and TC in serum (a). Analysis of HOMA-IR index (b). Body weight level was recorded every week throughout the study (c). The rats were rendered diabetic via IP injection of STZ (25 mg/kg body weight), and blood glucose levels were recorded after diabetes rats were supplemented with EOFAZ during the last 8 weeks (d). After hematoxylin–eosin staining, the pathological images of sections from the retina were taken under a microscope at ×40 magnification (e). ONL outer nuclear layer, OPL outer plexiform layer, INL inner nuclear layer, GCL ganglion cell layer. Data are expressed as mean ± SEM, n ≥ 6, **P < 0.01 vs. non-diabetic rats