Fig. 5

A PPAR-γ signal was involved in the inhibition effects of EOFAZ on RMCs gliosis induced by HG. GW9662 and RGZ were incubated alone or combined with EOFAZ in RMCs. The mRNA levels of GFAP, VEGF and PPAR-γ were detected via qRT-PCR (a, d). The protein expression of GFAP, VEGF and PPAR-γ was analyzed by Western blot analysis (b, c, e, f). Data are expressed as mean ± SEM. n = 3. *P < 0.05, **P < 0.01 vs. control group, ^#P < 0.05, ^##P < 0.01 vs. HG group, ^$P < 0.05 vs.HG + EOFAZ group