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Fig. 3 | Chinese Medicine

Fig. 3

From: Cryptotanshinone from Salvia miltiorrhiza Bunge (Danshen) inhibited inflammatory responses via TLR4/MyD88 signaling pathway

Fig. 3

Effects of CPT on lipopolysaccharide (LPS)-stimulated phosphoinositide 3-kinase (PI3K)/AKT and Nuclear factor erythroid 2 related factor 2 (Nrf2) pathways in RAW264.7 cells. The cells were pretreated with CPT (0, 2, 4, 8 μM) for 1 h before exposure to LPS (1 μg/mL) for 8 h. The protein expressions of a, b PI3K, a, c AKT, d, e Kelch-like ECH-associated protein 1 (Keap-1), d, f Nrf2, d, g Heme oxygenase-1 (HO-1), and d, h NAD(P)H: quinone oxidoreductase-1 (NQO1) were determined by immunoblotting. n = 3. *p < 0.05, **p < 0.01, ***p < 0.001 compared with LPS alone group

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