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Fig. 2 | Chinese Medicine

Fig. 2

From: Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo

Fig. 2

Effects of SK, 4-OHT, and the combination on cell apoptosis. a Representative dot-plots from cytometrically illustrating apoptotic status in MCF-7 cells. b Statistic analysis of apoptotic cells (percentage of cells in Q2 and Q3). c Statistic analysis of early (E, percentage of cells in Q3) and late (L, percentage of cells in Q2) apoptotic cells. d Representative dot-plots from cytometrically illustrating apoptotic status in MDA-MB-435S cells. e Statistic analysis of apoptotic cells (percentage of cells in Q2 and Q3). f Statistic analysis of early (E, percentage of cells in Q3) and late (L, percentage of cells in Q2) apoptotic cells. Images are representative of three independent experiments. Data are mean ± S.E.M. from three independent experiments (*P < 0.05, **P < 0.01 compared with the negative control; ##P < 0.01 compared with the combination group)

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